A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 31

Pharmacokinetic parameters of Dau and DS after i.v. administration in beagle dogs (6 mg/kg, ) [30].

Parameters	DS	Dau
α/h^−1	32 13	16 6
β/h^−1	0.24 0.07	0.27 0.07
/h	0.026 0.014	0.049 0.016
/h	3.1 0.9	2.7 0.6
/h^−1	3.3 1.5	2.1 0.9
/h^−1	2.3 0.4	2.0 0.5
/h^−1	27 12	12 5
MRT/h	8.0 1.9	7.5 1.0
/L/kg	12 3	16 3
AUC/mg·h/L	2.17 0.17	1.48 0.17
/mg/L	3.8 0.7	2.26 0.23

, , and versus DS.