A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 36

Pharmacokinetic parameters asarinin, sesamin, helioxanthin, and savinin after oral administration of Acanthopanax sessiliflorus extract in rats () [34].

Parameters	Asarinin	Sesamin	Helioxanthin	Savinin
(ng/mL)	392.8 51.2	1285.6 117.4	39.1 4.1	121.2 21.2
(h)	2.50 0.15	1.94 0.28	2.22 0.48	2.83 0.29
(h)	6.08 1.10	11.69 0.50	7.16 0.52	6.26 0.57
AUC (ng h/mL)	1839.9 402.2	14822.1 1852.4	171.5 16.8	964.1 119.0
AUC (ng h/mL)	1933.9 446.2	16783.3 1843.3	186.1 17.0	1043.8 109.4
LLOQ (ng/mL)	10.80	106	1.960	8.320