A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 46

Pharmacokinetic parameters of WA and WLD after oral administration of WSE in mice [43].

Parameter	Withaferin A	Withanolide A
(ng/mL)	16.69 4.02	26.59 4.47
(min)	20 (20–30)	10 (10–30)
(min)	59.92 15.90	45.22 9.95
AUC (ng/mL min)	1572.27 57.80	2458.47 212.72
AUC (ng/mL min)	1673.10 54.53	2516.41 212.10
CL (mL/min/kg)	274.10 9.10	191.10 16.74

Data expressed as mean SD () except mentioned as median.