Review Article

A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 5

Pharmacokinetic parameters of luteolin-7-O-gentiobioside, luteolin-7-O-β-d-glucoside, and luteolin-7-O-β-d-glucuronide after i.v. administration of Kudiezi injection to beagle dogs () [8].

Analytes (ng h/mL) (ng h/mL) (h) (h) (ng/mL)LLOQ (ng/mL)

Luteolin-7-O-gentiobioside54.42 9.9056.89 10.151.103 0.2211.014 0.03443.82 13.681.0
Luteolin-7-O--d-glucoside56.71 7.8759.23 8.301.330 0.2670.944 0.13651.22 14.361.0
Luteolin-7-O-d-glucuronide228.8 19.6238.7 19.71.184 0.8771.000 0.000249.0 58.24.0