A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 56

Pharmacokinetic parameters of SEI after i.v. administration of SEI in rat plasma () [52].

Parameters	Dose
	18 (mg/kg)	36 (mg/kg)	72 (mg/kg)
AUC (mg min/mL)	454.26 41.73	807.72 82.70	1796.51 201.03
AUC (mg min/mL)	449.39 36.95	797.02 84.53	1773.63 191.35
MRT (min)	36.85 6.95	38.68 3.30	42.96 8.99
MRT (min)	34.16 4.08	34.96 2.27	39.73 7.00
(min)	38.26 8.47	43.54 6.94	39.69 9.17
(mL/kg)	2181.40 373.98	2839.20 707.02	2291.80 486.14
CL (mL/min/kg)	39.80 3.70	44.60 5.13	40.02 4.66