A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

Table 58

The noncompartmental PK parameters of solasonine after oral and sublingual i.v. administration of 30 and 3 mg/kg, respectively () [53].

Parameter	Dose
	p.o. (30 mg/kg)	i.v. (3 mg/kg)
(h)	0.7 0.3	0.1
(μg/L)	172.3 87.1	2777.5 1227.7
(h)	3.5 1.8	1.4 0.2
/ (L/kg)	275.4 170.2	1.5 0.2
CL/ (L/h/kg)	67.3 59.8	0.8 0.1
AUC (μg/L·h)	615.7 345.0	4101.1 719.3
AUC (μg/L·h)	688.1 413.91	4118.9 717.8
(%)	1.7	100