Table of Contents
Organic Chemistry International
Volume 2010, Article ID 648589, 7 pages
Research Article

Synthesis and Antimicrobial Studies of Tridentate Schiff Base Ligands with Pyrazolone Moiety and Their Metal Complexes

Department of Chemistry, Pondicherry University, Puducherry 605 014, India

Received 8 September 2010; Revised 23 October 2010; Accepted 2 November 2010

Academic Editor: Feihe Huang

Copyright © 2010 Ramasamy Jayarajan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Synthesis, characterization, and antimicrobial activity of tridentate Schiffbase ligands containing pyrazolone moiety (3a and 3b) and their transition metal complexes of VO(II), Cu(II), Fe(III), and Co(II) 4ah have been investigated. The complexes show enhanced antibacterial activity against S. aureus, E. coli, and S. typhi and antifungal activity against C. albicans, Rhizopus sp., and A. niger compared to the ligands.