Research Article
2-Pyrrolidinones and 3-Pyrrolin-2-ones: A Study on the Chemical Reactivity of These Structural Moieties
Scheme 3
Reagents and conditions: (a) NaBH4 (1.1 equiv), MeOH (r.t., 5 h); (b) (i) LDA (1.1 equiv), THF (−78°C, 30 min), (ii) PhCHO [1.1 equiv, −78°C (2.5 h), r.t. (1 h)].