Research Article

Copper(I)-BINOL Catalyzed Domino Synthesis of 1,4-Benzoxathiines through 𝐂 ( 𝐚 𝐫 𝐲 𝐥 ) -O Bond Formation

Table 4

Scope of the domino reaction with various epoxides and o-iodothiophenol for the synthesis of 1,4-benzoxathiine moietiesa.

980765.tab.004a

EntryEpoxide1,4-benzoxathiinesTime (h)Yield (%)b

1980765.tab.004b980765.tab.004c7260
2980765.tab.004d980765.tab.004e7543
3980765.tab.004f980765.tab.004g7827
4980765.tab.004h980765.tab.004i8424

aReactions were carried out in pressure tube; bisolated yield.