Research Article

L-Tyrosine as an Eco-Friendly and Efficient Catalyst for Knoevenagel Condensation of Arylaldehydes with Meldrum’s Acid in Solvent-Free Condition under Grindstone Method

Scheme 1

Knoevenagel condensation of arylaldehydes with meldrum’s acid in the presence of L-tyrosine in solvent-free condition under grindstone method. (a) R = C6H5, (b) R = CH3–C6H4, (c) R = OCH3–C6H4, (d) P-(Me2N)–C6H4, (e) P-(OH)–C6H4, (f) P-(Cl)–C6H4, (g) P-(NO2)–C6H4, (h) O-(NO2)–C6H4, (i) O-(Cl)–C6H4, and (j) M-(OH)–C6H4.
191584.sch.001