Organic Chemistry International / 2012 / Article / Tab 2

Research Article

An Expeditious and Safe Synthesis of Some Exocyclic α,β-Unsaturated Ketones by Microwave-Assisted Condensation of Cyclic Ketones with Aromatic Aldehydes over Anhydrous Potassium Carbonate

Table 2

Microwave-assisted condensation of 1-thiochroman-4-one (1e) with aromatic aldehydes.

EntryCatalystAr of aldehydeTime (min.)Product
Yield (%)M.P
Obs. (Lit.) [Reference]

Anhy. K2CO3C6H51.53a7260
(59–61) [63]
Anhy. K2CO34-Cl–C6H41.53b78110
Anhy. K2CO34-MeO–C6H41.52y69112-113
(113) [59]
Neutral aluminaC6H51.52z55104-105
(105) [59]
Neutral alumina4-Cl–C6H41.52z159138-139
(138-139) [59]
Neutral alumina4-MeO–C6H41.52y52112-113
(113) [59]

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.