An Expeditious and Safe Synthesis of Some Exocyclic α,β-Unsaturated Ketones by Microwave-Assisted Condensation of Cyclic Ketones with Aromatic Aldehydes over Anhydrous Potassium Carbonate

Table 3

Microwave-assisted condensation of cycloalkanones with aromatic aldehydes and cinnamaldehyde over anhy. K₂CO₃.

Entry	Ketone (1)	Ar of aldehyde	Time (min.)	Product (5)	Yield (%)	M.P; Obs. (Lit.) [Reference]
(1)	4a	C6H5–	1.5	5a	85	190; (190) [64]
(2)	4a	4-MeO–C6H4–	1.5	5b	78	215; (215) [64]
(3)	4a	4-Cl–C6H4–	1.5	5c	86	228-229; (229-230) [64]
(4)	4a	E-C6H5CH=CH–	1.5	5d	87	220; (220-221) [64]
(5)	4b	C6H5–	1.5	5e	82	155; (155) [64]
(6)	4b	4-MeO–C6H4–	1.5	5f	78	213; (213) [64]
(7)	4b	4-Cl–C6H4–	1.5	5g	88	141-142; (138) [64]
(8)	4b	E-C6H5CH=CH–	1.5	5h	82	176-177; (178) [64]
(9)	4c	C6H5–	1.5	5i	85	108; 106.5–108 [65]
(10)	4c	E-C6H5CH=CH–	1.5	5j	81	204–206; 207-208 [65]