Table of Contents
Organic Chemistry International
Volume 2012 (2012), Article ID 498521, 5 pages
http://dx.doi.org/10.1155/2012/498521
Research Article

Highly Efficient and Facile Method for Synthesis of 2-Substituted Benzimidazoles via Reductive Cyclization of O-Nitroaniline and Aryl Aldehydes

Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan 87317, Iran

Received 15 August 2012; Accepted 14 October 2012

Academic Editor: Paul Watts

Copyright © 2012 Hossein Naeimi and Nasrin Alishahi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A versatile and convenient synthesis of 2-substituted benzimidazoles, using o-nitroaniline as starting material with several aryl aldehydes, has been accomplished by using a small amount of a reluctant agent. The reaction was carried out under very mild conditions at room temperature. The yields obtained are very good in reasonably short reaction times.