Synthesis of Bis-2,3-dihydroquinazolin-4(1H)-ones and 2,3-Dihydroquinazolin-4(1H)-ones Derivatives with the Aid of Silica-Supported Preyssler Nanoparticles

Table 4

Synthesis of bis-2,3-dihydroquinazolin-4(1H)-ones in the presence of Silica-Supported Preyssler Nanoparticles catalyst in water and/or ethanol solvents under reflux conditions.

Entry	Aldehyde	Amine	Product	Time (h)		^aYield (%)
				H2O	EtOH	EtOH	H2O
1				3	4	67	70.5
2				3	6	70	73.5
3				4	9	60	64.5
4				5.5	11.5	52	56.5
5				2.5	5	63	67
6		CH3CH2NH2		3.5	5	65	71
7				3.5	5.5	67	72.5
8		NH3		3.5	6	63	66.5
9		NH3		3.5	7.5	62.5	67.5

 ^aIsolated yield.