Synthesis of Bis-2,3-dihydroquinazolin-4(1H)-ones and 2,3-Dihydroquinazolin-4(1H)-ones Derivatives with the Aid of Silica-Supported Preyssler Nanoparticles

Table 5

Solvent effects in the reaction of C₂H₅NH₂, isatoic anhydride, and terephthaldehyde for the synthesis of (2,2′-(1,4-phenylene)bis(3-(4-ethylphenyl)-2,3-dihydroquinazolin-4(1H)-one)) (Table 4, Entry 2, product 2b) in the presence of silica-supported preyssler nanoparticles catalyst.

Entry	Solvent	^bYield (%)	Time (h)
1	H2O	73.5	3
2	TBAB	61	8
3	C2H5OH	70	6
4	CH3OH	37	12
5	CH3CN	27	20
6	CH2Cl2	—	—
7	C6H5CH3	—	—
8	CCl4	—	—

 ^bIsolated yield.