Research Article

Catalytic Synthesis of -Aminonitriles Using Nano Copper Ferrite under Green Conditions

Table 3

Synthesis of 2-(4-Nitrophenyl)-2-(phenylamino)acetonitrile (4i) in the presence of (nano copper ferrite (CuFe2O4) catalyst with AcOH) and various solvents at room temperature (solvent optimization).

EntrySolvent aYield (%)

1H2O98
2C2H5OH59
3DMF81
4DMSO80
5CHCl377
6C6H5CH379
7CH3OH72
8CH2Cl278
9CCl483
10C6H676
11n-Hexane69

Isolated yields.