Table of Contents
Organic Chemistry International
Volume 2014 (2014), Article ID 403803, 5 pages
Research Article

An Ultrasound Mediated Green Synthesis of Benzimidazolylthiounsaturatednitriles Using Water as a Green Solvent

Department of Chemistry, College of Engineering, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad 500 085, India

Received 8 July 2014; Revised 27 September 2014; Accepted 20 October 2014; Published 9 November 2014

Academic Editor: Jonathan White

Copyright © 2014 Sadhu Srinivas Rao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Reaction of 2-cyanothiomethylbenzimidazole  1 with an aromatic aldehydes in water under ultrasonic irradiation for 10–13 min gave the corresponding unsaturated nitriles 2ah which is an efficient and simple method under green conditions. The unsaturated nitrile derivatives were obtained in 86–98% yield with a short reaction time without any tedious workup procedures.