Table of Contents
Organic Chemistry International
Volume 2014, Article ID 761209, 5 pages
Research Article

An Efficient One-Pot Multi-Component Synthesis of 3,4-Dihydropyrimidin-2-(1H)-Ones/Thiones Catalyzed by Bismuth (III) Sulfate Trihydrate under Solvent-Free Conditions

Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, Iran

Received 17 October 2013; Revised 8 January 2014; Accepted 8 January 2014; Published 13 March 2014

Academic Editor: Ashraf Aly Shehata

Copyright © 2014 Farhad Hatamjafari. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A convenient and efficient protocol for the one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives of aldehydes, and 1,3-dicarbonyl compounds with Bismuth (III) sulfate trihydrate as the catalyst was described. We had the advantages of good performance, simplicity, and short time reaction under solvent-free conditions. The catalyst can be repeatedly reused without loss of its activity.