Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.5121pt" id="M1" height="17.3139pt" version="1.1" viewBox="-0.0657574 -12.8018 188.37 17.3139" width="188.37pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><path id="g190-41" d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 611 70 451 70 272V271C70 90 136 -71 282 -169L300 -147Z"/></g><g transform="matrix(.018,0,0,-0.018,6.211,0)"><path id="g190-73" d="M729 650H468V622C546 615 554 610 554 527V365H213V527C213 610 221 616 297 622V650H38V622C120 616 128 611 128 527V123C128 39 120 34 40 28V0H303V28C221 34 213 40 213 123V322H554V123C554 39 546 34 460 28V0H728V28C647 34 639 39 639 123V527C639 610 647 615 729 622V650Z"/></g><g transform="matrix(.013,0,0,-0.013,19.961,4.308)"><path id="g187-213" d="M345 0V33C260 38 258 46 258 122V635C174 612 105 594 35 583V554L87 550C124 546 130 539 130 494V122C130 46 127 38 42 33V0H345Z"/></g><g transform="matrix(.013,0,0,-0.013,24.454,4.308)"><path id="g187-166" d="M496 176V231H406V629H337C242 511 133 363 25 211V176H279V113C279 53 274 40 189 33V0H487V33C413 40 406 49 406 109V176H496ZM279 231H103C166 334 228 422 277 488H279V231Z"/></g><g transform="matrix(.018,0,0,-0.018,31.701,0)"><path id="g190-92" d="M290 -163V-135C183 -126 181 -122 181 -44V584C181 662 184 667 290 675V703H120V-163H290Z"/></g><g transform="matrix(.018,0,0,-0.018,37.871,0)"><path id="g190-79" d="M719 650H483V622C553 619 576 606 581 560C585 532 588 487 588 394V148H585L167 650H20V622C67 618 88 610 109 585C127 562 129 557 129 484V264C129 173 126 124 123 93C118 44 92 31 35 28V0H272V28C204 32 181 44 176 95C173 124 170 172 170 264V515H172L598 -9H629V394C629 487 631 532 635 563C639 606 663 619 719 622V650Z"/></g><g transform="matrix(.018,0,0,-0.018,50.692,0)"><path id="g190-98" d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 237 25 277 52C282 35 288 21 301 8C312 -3 333 -12 348 -12L433 39ZM275 84C256 65 221 48 195 48C164 48 124 73 124 124C124 161 146 180 185 198C206 208 254 229 275 240V84Z"/></g><g transform="matrix(.018,0,0,-0.018,58.645,0)"><path id="g190-81" d="M46 650V622C120 617 128 613 128 525V125C128 42 120 34 40 28V0H311V28C221 34 212 39 212 124V281L286 262C297 261 316 261 331 263C429 275 526 338 526 468C526 533 501 579 462 609C422 638 364 650 293 650H46ZM212 559C212 588 215 600 223 606C230 613 251 618 279 618C361 618 430 572 430 464C430 337 350 302 285 302C252 302 225 309 212 314V559Z"/></g><g transform="matrix(.013,0,0,-0.013,68.751,4.308)"><path id="g187-161" d="M137 515H396L428 613L422 623H104L59 307C80 314 123 327 169 327C260 327 316 267 316 175C316 98 286 45 221 45C166 45 118 84 94 106C81 117 70 121 59 112C41 99 27 77 27 61C27 46 32 36 52 20C73 2 115 -12 155 -12C216 -11 287 14 343 54C413 104 444 164 444 227C444 316 371 399 243 399C217 399 160 384 111 365L137 515Z"/></g><g transform="matrix(.018,0,0,-0.018,75.491,0)"><path id="g190-88" d="M956 650H736V622C814 613 818 602 804 542C789 471 733 275 691 141H689C628 314 570 476 514 641H485C434 478 377 312 323 142H321C277 284 238 419 199 554C184 605 186 613 259 622V650H16V622C77 615 92 606 117 524C172 346 228 170 281 -11H312C363 151 419 312 475 488H477C528 343 597 150 652 -11H683C765 269 826 458 848 522C878 605 887 613 956 622V650Z"/></g><g transform="matrix(.013,0,0,-0.013,92.92,4.308)"><path id="g187-232" d="M295 385C328 406 353 421 370 436C390 452 402 476 402 502C402 578 343 635 239 635H238C172 635 124 606 97 574L48 506L74 482C102 521 141 558 194 558C239 558 278 530 278 469S219 366 134 339L141 307C156 311 177 313 195 313C246 313 314 274 314 177C314 79 276 43 226 43C166 43 117 89 95 108C82 118 70 116 58 107C45 97 29 80 29 61C29 47 36 34 53 21C73 5 114 -12 164 -12C226 -12 444 54 444 224C444 299 391 365 295 383V385Z"/></g><g transform="matrix(.013,0,0,-0.013,99.106,4.308)"><path id="g187-254" d="M264 635C97 635 40 460 40 311C40 167 94 -12 262 -12C431 -12 484 166 484 312C484 457 431 635 264 635ZM261 595C330 595 347 450 347 314C347 174 330 28 263 28C195 28 177 174 177 315C177 450 194 595 261 595Z"/></g><g transform="matrix(.018,0,0,-0.018,106.37,0)"><path id="g190-80" d="M381 665C170 665 44 498 44 318C44 125 188 -15 369 -15C552 -15 703 117 703 333C703 534 550 665 381 665ZM359 629C491 629 601 517 601 306C601 114 502 21 390 21C249 21 146 158 146 346S248 629 359 629Z"/></g><g transform="matrix(.013,0,0,-0.013,119.779,4.308)"><use xlink:href="#g187-213"/></g><g transform="matrix(.013,0,0,-0.013,124.411,4.308)"><use xlink:href="#g187-213"/></g><g transform="matrix(.013,0,0,-0.013,129.13,4.308)"><use xlink:href="#g187-254"/></g><g transform="matrix(.018,0,0,-0.018,136.407,0)"><path id="g190-94" d="M226 -163V703H56V676C162 667 165 662 165 584V-43C165 -122 162 -126 56 -136V-163H226Z"/></g><g transform="matrix(.018,0,0,-0.018,142.577,0)"><path id="g190-48" d="M298 665H241L25 -44H81L298 665Z"/></g><g transform="matrix(.018,0,0,-0.018,148.542,0)"><path id="g190-84" d="M409 504C401 567 396 607 392 642C354 654 312 665 266 665C137 665 60 583 60 487C60 374 161 325 225 290C300 250 355 215 355 141C355 68 311 21 235 21C131 21 86 122 71 183L41 176C48 128 61 42 68 21C78 16 93 8 118 0C142 -7 175 -15 216 -15C349 -15 438 69 438 174C438 287 344 333 265 374C186 414 138 449 138 522C138 576 172 631 249 631C336 631 363 562 380 499L409 504Z"/></g><g transform="matrix(.018,0,0,-0.018,156.911,0)"><path id="g190-106" d="M135 536C164 536 186 560 186 587C186 617 164 639 136 639C109 639 85 617 85 587C85 560 109 536 135 536ZM252 0V26C188 32 181 38 181 106V451C138 433 90 420 39 412V388C99 379 102 374 102 312V106C102 38 95 32 32 26V0H252Z"/></g><g transform="matrix(.018,0,0,-0.018,161.704,0)"><use xlink:href="#g190-80"/></g><g transform="matrix(.013,0,0,-0.013,175.163,4.308)"><path id="g187-243" d="M442 172C405 109 393 108 333 108H171L289 222C383 315 430 374 430 457C430 569 349 635 249 635C187 635 134 610 97 573L34 478L61 455C93 502 136 542 196 542C265 542 300 491 300 422C300 346 261 273 191 190C142 132 84 76 31 25V0H432C443 42 455 105 471 163L442 172Z"/></g><g transform="matrix(.018,0,0,-0.018,182.028,0)"><path id="g190-42" d="M275 271C275 451 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 269V271Z"/></g></svg> as an Eco-Friendly, Inexpensive, and Efficient Catalyst

<table>Synthesis of ibuprofen using Silica-Supported Preyssler Nanoparticles (H<sub>14</sub>[NaP<sub>5</sub>W<sub>30</sub>O<sub>110</sub>]/SiO<sub>2</sub>) (SPNPs) using ethanol and pyridine in their reactions.</table>

Organic Chemistry International

sch1

Scheme 1

Scheme 1: Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles <svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.5121pt" id="M1" height="17.3139pt" version="1.1" viewBox="-0.0657574 -12.8018 188.37 17.3139" width="188.37pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><path id="g190-41" d="M300 -147C201 -63 143 98 143 270S200 602 300 686L282 710C136 611 70 451 70 272V271C70 90 136 -71 282 -169L300 -147Z"/></g><g transform="matrix(.018,0,0,-0.018,6.211,0)"><path id="g190-73" d="M729 650H468V622C546 615 554 610 554 527V365H213V527C213 610 221 616 297 622V650H38V622C120 616 128 611 128 527V123C128 39 120 34 40 28V0H303V28C221 34 213 40 213 123V322H554V123C554 39 546 34 460 28V0H728V28C647 34 639 39 639 123V527C639 610 647 615 729 622V650Z"/></g><g transform="matrix(.013,0,0,-0.013,19.961,4.308)"><path id="g187-213" d="M345 0V33C260 38 258 46 258 122V635C174 612 105 594 35 583V554L87 550C124 546 130 539 130 494V122C130 46 127 38 42 33V0H345Z"/></g><g transform="matrix(.013,0,0,-0.013,24.454,4.308)"><path id="g187-166" d="M496 176V231H406V629H337C242 511 133 363 25 211V176H279V113C279 53 274 40 189 33V0H487V33C413 40 406 49 406 109V176H496ZM279 231H103C166 334 228 422 277 488H279V231Z"/></g><g transform="matrix(.018,0,0,-0.018,31.701,0)"><path id="g190-92" d="M290 -163V-135C183 -126 181 -122 181 -44V584C181 662 184 667 290 675V703H120V-163H290Z"/></g><g transform="matrix(.018,0,0,-0.018,37.871,0)"><path id="g190-79" d="M719 650H483V622C553 619 576 606 581 560C585 532 588 487 588 394V148H585L167 650H20V622C67 618 88 610 109 585C127 562 129 557 129 484V264C129 173 126 124 123 93C118 44 92 31 35 28V0H272V28C204 32 181 44 176 95C173 124 170 172 170 264V515H172L598 -9H629V394C629 487 631 532 635 563C639 606 663 619 719 622V650Z"/></g><g transform="matrix(.018,0,0,-0.018,50.692,0)"><path id="g190-98" d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 237 25 277 52C282 35 288 21 301 8C312 -3 333 -12 348 -12L433 39ZM275 84C256 65 221 48 195 48C164 48 124 73 124 124C124 161 146 180 185 198C206 208 254 229 275 240V84Z"/></g><g transform="matrix(.018,0,0,-0.018,58.645,0)"><path id="g190-81" d="M46 650V622C120 617 128 613 128 525V125C128 42 120 34 40 28V0H311V28C221 34 212 39 212 124V281L286 262C297 261 316 261 331 263C429 275 526 338 526 468C526 533 501 579 462 609C422 638 364 650 293 650H46ZM212 559C212 588 215 600 223 606C230 613 251 618 279 618C361 618 430 572 430 464C430 337 350 302 285 302C252 302 225 309 212 314V559Z"/></g><g transform="matrix(.013,0,0,-0.013,68.751,4.308)"><path id="g187-161" d="M137 515H396L428 613L422 623H104L59 307C80 314 123 327 169 327C260 327 316 267 316 175C316 98 286 45 221 45C166 45 118 84 94 106C81 117 70 121 59 112C41 99 27 77 27 61C27 46 32 36 52 20C73 2 115 -12 155 -12C216 -11 287 14 343 54C413 104 444 164 444 227C444 316 371 399 243 399C217 399 160 384 111 365L137 515Z"/></g><g transform="matrix(.018,0,0,-0.018,75.491,0)"><path id="g190-88" d="M956 650H736V622C814 613 818 602 804 542C789 471 733 275 691 141H689C628 314 570 476 514 641H485C434 478 377 312 323 142H321C277 284 238 419 199 554C184 605 186 613 259 622V650H16V622C77 615 92 606 117 524C172 346 228 170 281 -11H312C363 151 419 312 475 488H477C528 343 597 150 652 -11H683C765 269 826 458 848 522C878 605 887 613 956 622V650Z"/></g><g transform="matrix(.013,0,0,-0.013,92.92,4.308)"><path id="g187-232" d="M295 385C328 406 353 421 370 436C390 452 402 476 402 502C402 578 343 635 239 635H238C172 635 124 606 97 574L48 506L74 482C102 521 141 558 194 558C239 558 278 530 278 469S219 366 134 339L141 307C156 311 177 313 195 313C246 313 314 274 314 177C314 79 276 43 226 43C166 43 117 89 95 108C82 118 70 116 58 107C45 97 29 80 29 61C29 47 36 34 53 21C73 5 114 -12 164 -12C226 -12 444 54 444 224C444 299 391 365 295 383V385Z"/></g><g transform="matrix(.013,0,0,-0.013,99.106,4.308)"><path id="g187-254" d="M264 635C97 635 40 460 40 311C40 167 94 -12 262 -12C431 -12 484 166 484 312C484 457 431 635 264 635ZM261 595C330 595 347 450 347 314C347 174 330 28 263 28C195 28 177 174 177 315C177 450 194 595 261 595Z"/></g><g transform="matrix(.018,0,0,-0.018,106.37,0)"><path id="g190-80" d="M381 665C170 665 44 498 44 318C44 125 188 -15 369 -15C552 -15 703 117 703 333C703 534 550 665 381 665ZM359 629C491 629 601 517 601 306C601 114 502 21 390 21C249 21 146 158 146 346S248 629 359 629Z"/></g><g transform="matrix(.013,0,0,-0.013,119.779,4.308)"><use xlink:href="#g187-213"/></g><g transform="matrix(.013,0,0,-0.013,124.411,4.308)"><use xlink:href="#g187-213"/></g><g transform="matrix(.013,0,0,-0.013,129.13,4.308)"><use xlink:href="#g187-254"/></g><g transform="matrix(.018,0,0,-0.018,136.407,0)"><path id="g190-94" d="M226 -163V703H56V676C162 667 165 662 165 584V-43C165 -122 162 -126 56 -136V-163H226Z"/></g><g transform="matrix(.018,0,0,-0.018,142.577,0)"><path id="g190-48" d="M298 665H241L25 -44H81L298 665Z"/></g><g transform="matrix(.018,0,0,-0.018,148.542,0)"><path id="g190-84" d="M409 504C401 567 396 607 392 642C354 654 312 665 266 665C137 665 60 583 60 487C60 374 161 325 225 290C300 250 355 215 355 141C355 68 311 21 235 21C131 21 86 122 71 183L41 176C48 128 61 42 68 21C78 16 93 8 118 0C142 -7 175 -15 216 -15C349 -15 438 69 438 174C438 287 344 333 265 374C186 414 138 449 138 522C138 576 172 631 249 631C336 631 363 562 380 499L409 504Z"/></g><g transform="matrix(.018,0,0,-0.018,156.911,0)"><path id="g190-106" d="M135 536C164 536 186 560 186 587C186 617 164 639 136 639C109 639 85 617 85 587C85 560 109 536 135 536ZM252 0V26C188 32 181 38 181 106V451C138 433 90 420 39 412V388C99 379 102 374 102 312V106C102 38 95 32 32 26V0H252Z"/></g><g transform="matrix(.018,0,0,-0.018,161.704,0)"><use xlink:href="#g190-80"/></g><g transform="matrix(.013,0,0,-0.013,175.163,4.308)"><path id="g187-243" d="M442 172C405 109 393 108 333 108H171L289 222C383 315 430 374 430 457C430 569 349 635 249 635C187 635 134 610 97 573L34 478L61 455C93 502 136 542 196 542C265 542 300 491 300 422C300 346 261 273 191 190C142 132 84 76 31 25V0H432C443 42 455 105 471 163L442 172Z"/></g><g transform="matrix(.018,0,0,-0.018,182.028,0)"><path id="g190-42" d="M275 271C275 451 212 609 64 710L45 686C145 604 203 442 203 270S147 -63 45 -147L64 -170C213 -68 275 89 275 269V271Z"/></g></svg> as an Eco-Friendly, Inexpensive, and Efficient Catalyst 

Organic Chemistry International

Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles as an Eco-Friendly, Inexpensive, and Efficient Catalyst

Scheme 1