Table of Contents
Organic Chemistry International
Volume 2016 (2016), Article ID 4705809, 8 pages
Research Article

Synthesis of New Energetic Materials and Ionic Liquids Derived from Metronidazole

Executive Committee Deputy of Industrial Affairs, Mexican Chemical Society, Barranca del Muerto No. 26, Colonia Crédito Constructor, Delegación Benito Juárez, 03940 Mexico City, DF, Mexico

Received 25 October 2015; Accepted 16 December 2015

Academic Editor: Kirpal Bisht

Copyright © 2016 Miguel A. Romero. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Simple and efficient synthetic procedures were established for the preparation of new energetic covalent compounds, salts, and protonated ionic liquids based on the readily available antimicrobial agent metronidazole. Some of these materials exhibit the desirable properties of energetic materials and energetic ionic liquids, such as low vapor pressure, low melting point, good chemical and thermal stability, and high energetic content. For each of the relevant compounds prepared, thermal stability was determined by differential scanning calorimetry. Some of these compounds may be considered promising precursors of pharmaceuticals such as antimicrobial, antiparasitic, antifungal, antineoplastic agents, or enzyme inhibitors.