Pediatric Diabetes

Research Article

Adolescents and Young Adults with Type 1 Diabetes Present Changes in Arterial Compliance and Resistance and Increased Arterial Stiffness

Table 2

Peripheral and central blood pressure, hemodynamic parameters, and arterial stiffness indexes between the control and diabetes groups.


Variables	Control, N = 45	T1DM, N = 45	P-value

Peripheral blood pressure
SBPp (mmHg)	113.7 ± 9.79	118.20 ± 15.26	0.3710^w
DBPp (mmHg)	70.55 ± 8.58	74.25 ± 12.10	0.3247^w
MAPp (mmHg)	90.21 ± 8.26	94.04 ± 12.11	0.2037^w
PPp (mmHg)	43.10 ± 7.36	43.46 ± 12.82	0.8940^w
Central blood pressure (aorta)
SBPc (mmHg)	101.2 ± 9.10	105.9 ± 14.74	0.1532^w
DBPc (mmHg)	72.12 ± 8.51	76.34 ± 12.66	0.2585^w
MAPp (mmHg)	81.82 ± 8.22	86.20 ± 12.67	0.1676^w
PPc (mmHg)	29.09 ± 6.12	30.53 ± 8.19	0.5914^w
Hemodynamic parameters
Systolic volume (ml)	61.50 ± 15.30	55.60 ± 14.14	0.0538^w
Cardiac output (l/min)	4.69 ± 0.59	4.68 ± 0.64	0.6805^w
Cardiac index (l/min/m²)	3.07 ± 0.45	2.95 ± 0.50	0.1163^w
Heart rate (bpm)	78.11 ± 13.75	87.10 ± 17.70	0.0086^t
Arterial stiffness
Alx@75 (%)	20.16 ± 9.95	24.96 ± 8.88	0.0177^t
Reflection coefficient (%)	55.82 ± 7.09	58.63 ± 9.23	0.0373^w
Augmentation pressure (mmHg)	5.64 ± 2.46	7.34 ± 4.67	0.1199^w
Pulse wave velocity (m/s)	4.64 ± 0.33	4.77 ± 0.54	0.4382^w

Data are represented as mean ± SD. SBPp, peripheral systolic blood pressure; DBPp, peripheral diastolic blood pressure; MAP, mean arterial pressure; PPp, peripheral pulse pressure; SBPc, central systolic blood pressure; DBPc, central diastolic blood pressure; PPc, central pulse pressure; SV, Stroke volume; AIx@75, augmentation index corrected for heart rate of 75 bpm. w = Mann–Whitney test and t = Student’s t-test for independent samples. Bold values indicate the variables are significant.