Table of Contents
Physiology Journal
Volume 2013 (2013), Article ID 539076, 6 pages
http://dx.doi.org/10.1155/2013/539076
Clinical Study

Combined Lung Transfer of NO and CO in Patients Receiving Methotrexate or Bleomycin Therapy Compared to Normal Subjects

1Pulmonary Function Testing Department, Lyon University Hospital, 165 Chemin du Grand-Revoyet, 69 495 Pierre-Bénite Cedex, France
2UCBL1 FRE CNRS 3310, 7 Passage du Vercors, 69367 Lyon Cedex, France
3Respiratory Diseases Department, Lyon University Hospital, 165 Chemin du Grand-Revoyet, 69495 Pierre-Bénite Cedex, France
4Lyon Sud-Charles Mérieux Medical Faculty, Claude Bernard Lyon 1 University, 69600 Oullins, France

Received 11 October 2012; Revised 26 November 2012; Accepted 24 December 2012

Academic Editor: Vincent Pialoux

Copyright © 2013 Chantal Viart-Ferber et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Spinel, C. Ochoa, C. Saavedra et al., “Methotrexate-induced pulmonary toxicity in psoriatic arthritis (PsA): case presentation and literature review,” Clinical Rheumatology, vol. 30, pp. 1379–1384, 2011. View at Publisher · View at Google Scholar
  2. H. Lioté, “Respiratory complications of new treatments for rheumatoid arthritis,” Revue des Maladies Respiratoires, vol. 21, pp. 1107–1115, 2004. View at Publisher · View at Google Scholar
  3. K. Shidara, D. Hoshi, E. Inoue et al., “Incidence of and risk factors for interstitial pneumonia in patients with rheumatoid arthritis in a large Japanese observational cohort, IORRA,” Modern Rheumatology, vol. 20, no. 3, pp. 280–286, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Imokawa, T. V. Colby, K. O. Leslie, and R. A. Helmers, “Methotrexate pneumonitis: review of the literature and histopathological findings in nine patients,” European Respiratory Journal, vol. 15, no. 2, pp. 373–381, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. L. Green, A. Schattner, and H. Berkenstadt, “Severe reversible interstitial pneumonitis induced by low dose methotrexate: report of a case and review of the literature,” Journal of Rheumatology, vol. 15, no. 1, pp. 110–112, 1988. View at Google Scholar · View at Scopus
  6. D. Sáenz Abad, F. J. Ruiz-Ruiz, S. Monón Ballarín, J. Mozota Duarte, and A. Marquina Barcos, “Pneumonitis associated to methotrexate,” Anales de Medicina Interna, vol. 25, no. 1, pp. 27–30, 2008. View at Google Scholar · View at Scopus
  7. H. Kameda, A. Okuyama, J. I. Tamaru, S. Itoyama, A. Iizuka, and T. Takeuchi, “Lymphomatoid granulomatosis and diffuse alveolar damage associated with methotrexate therapy in a patient with rheumatoid arthritis,” Clinical Rheumatology, vol. 26, no. 9, pp. 1585–1589, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. R. L. Mulder, N. M. Thِnissen, H. J. van der Pal et al., “Pulmonary function impairment measured by pulmonary function tests in long-term survivors of childhood cancer,” Thorax, vol. 66, pp. 1065–1071, 2011. View at Google Scholar
  9. E. F. Redente, K. M. Jacobsen, J. J. Solomon et al., “Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis,” American Journal of Physiology, vol. 301, pp. L510–L518, 2011. View at Google Scholar
  10. T. T. - Huang, M. M. Hudson, D. C. Stokes, M. J. Krasin, and S. L. Spunt, “Ness KK. Pulmonary outcomes in survivors of childhood cancer: a systematic review,” Chest, vol. 140, pp. 881–901, 2011. View at Google Scholar
  11. D. Jun, C. Garat, J. West et al., “The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation,” Stem Cells, vol. 29, no. 4, pp. 725–735, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Usman, Z. S. Faruqui, N. ud Din, and K. F. Zahid, “Bleomycin induced pulmonary toxicity in patients with germ cell tumours,” Journal of Ayub Medical College Abbottabad, vol. 22, pp. 35–37, 2010. View at Google Scholar
  13. M. Tashiro, K. Izumikawa, D. Yoshioka et al., “Lung fibrosis 10 years after cessation of bleomycin therapy,” Tohoku Journal of Experimental Medicine, vol. 216, no. 1, pp. 77–80, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. A. K. Ng, S. Li, D. Neuberg et al., “A prospective study of pulmonary function in Hodgkin's lymphoma patients,” Annals of Oncology, vol. 19, no. 10, pp. 1754–1758, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. M. K. Ferguson, J. J. Dignam, J. Siddique, W. T. Vigneswaran, and A. D. Celauro, “Diffusing capacity predicts long-term survival after lung resection for cancer,” European Journal Cardio-Thoracic Surgery, vol. 41, pp. 81–86, 2012. View at Publisher · View at Google Scholar
  16. B. Mahut, B. Chevalier-Bidaud, L. Plantier et al., “Diffusing capacity for carbon monoxide is linked to ventilatory demand in patients with chronic obstructive pulmonary disease,” Journal of Chronic Obstructive Pulmonary Disease, vol. 9, pp. 16–21, 2012. View at Publisher · View at Google Scholar
  17. S. Trad, L. T. Huong du, C. Frances et al., “Impaired carbon monoxide diffusing capacity as a marker of limited systemic sclerosis,” European Journal of Internal Medicine, vol. 22, pp. 80–86, 2011. View at Google Scholar
  18. A. J. Lopes, D. Capone, R. Mogami, S. L. S. de Menezes, F. S. Guimarães, and R. A. Levy, “Systemic sclerosis-associated interstitial pneumonia: evaluation of pulmonary function over a five-year period,” Jornal Brasileiro de Pneumologia, vol. 37, no. 2, pp. 144–151, 2011. View at Google Scholar · View at Scopus
  19. J. S. Park, H. K. Kim, K. Kim, J. Kim, Y. M. Shim, and Y. S. Choi, “Prediction of acute pulmonary complications after resection of lung cancer in patients with preexisting interstitial lung disease,” Thoracic and Cardiovascular Surgeon, vol. 59, no. 3, pp. 148–152, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Launay, M. Humbert, A. Berezne et al., “Clinical characteristics and survival in systemic sclerosis-related pulmonary hypertension associated with interstitial lung disease pulmonary hypertension in scleroderma,” Chest, vol. 140, no. 4, pp. 1016–1024, 2011. View at Publisher · View at Google Scholar
  21. J. Michael, B. Hugues, and N. B. Pride, “Examination of the carbon monoxide diffusing capacity (DLCO) in relation to its KCO and Va components,” American Journal of Respiratory and Critical Care Medicine, vol. 186, pp. 132–139, 2012. View at Publisher · View at Google Scholar
  22. F. J. W. Roughton and R. E. Forster, “Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries,” Journal of Applied Physiology, vol. 11, no. 2, pp. 290–302, 1957. View at Google Scholar · View at Scopus
  23. F. J. W. Roughton, R. E. Forster, and L. Cander, “Rate at which carbon monoxide replaces oxygen from combination with human hemoglobin in solution and in the red cell,” Journal of Applied Physiology, vol. 11, no. 2, pp. 269–276, 1957. View at Google Scholar · View at Scopus
  24. H. Guenard, N. Varene, and P. Vaida, “Determination of lung capillary blood volume and membrane diffusing capacity in man by the measurements of NO and CO transfer,” Respiration Physiology, vol. 70, no. 1, pp. 113–120, 1987. View at Google Scholar · View at Scopus
  25. B. Aguilaniu, J. Maitre, S. Glénet, A. Gegout-Petit, and H. Guénard, “European reference equations for CO and NO lung transfer,” European Respiratory Journal, vol. 31, no. 5, pp. 1091–1097, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Guillot, J. Beillot, C. Meunier, and J. Dassonville, “Interpreting carbon monoxide transfer coefficient: significance and difficulties,” Revue des Maladies Respiratoires, vol. 22, no. 5, pp. 759–766, 2005. View at Google Scholar · View at Scopus
  27. B. Degano, M. Mittaine, H. Guénard et al., “Nitric oxide and carbon monoxide lung transfer in patients with advanced liver cirrhosis,” Journal of Applied Physiology, vol. 107, no. 1, pp. 139–143, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. E. F. Redente, K. M. Jacobsen, J. J. Solomon et al., “Age and sex dimorphisms contribute to the severity of bleomycine induced lung injury and fibrosis,” American Journal of Physiology, vol. 301, pp. L501–L508, 2011. View at Google Scholar
  29. D. Capone, A. Spanò, A. Gentile et al., “Are there differences in methotrexate kinetics between responding and nonresponding patients with rheumatoid arthritis?” BioDrugs, vol. 13, no. 5, pp. 373–379, 2000. View at Google Scholar · View at Scopus
  30. A. R. Phansalkar, C. M. Hanson, A. R. Shakir, R. L. Johnson Jr., and C. C. W. Hsia, “Nitric oxide diffusing capacity and alveolar microvascular recruitment in sarcoidosis,” American Journal of Respiratory and Critical Care Medicine, vol. 169, no. 9, pp. 1034–1040, 2004. View at Google Scholar · View at Scopus
  31. R. S. Harris, M. Hadian, D. R. Hess, Y. Chang, and J. G. Venegas, “Pulmonary artery occlusion increases the ratio of diffusing capacity for nitric oxide to carbon monoxide in prone sheep,” Chest, vol. 126, no. 2, pp. 559–565, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. C. Borland, Y. Cox, and T. Higenbottam, “Reduction of pulmonary capillary blood volume in patients with severe unexplained pulmonary hypertension,” Thorax, vol. 51, no. 8, pp. 855–856, 1996. View at Google Scholar · View at Scopus
  33. J. Moinard and H. Guenard, “Membrane diffusion of the lungs in patients with chronic renal failure,” European Respiratory Journal, vol. 6, no. 2, pp. 225–230, 1993. View at Google Scholar · View at Scopus
  34. C. Borland, “A place for TL,NO with TL,CO?” European Respiratory Journal, vol. 31, no. 5, pp. 918–919, 2008. View at Publisher · View at Google Scholar · View at Scopus