A Single Amino Acid Substitution in the Renal Betaine/GABA Transporter Prevents Trafficking to the Plasma Membrane
Figure 1
Incubation of MDCK cells for 3 h in hypertonic (Hyp) medium containing calyculin (0–30 nM), an inhibitor of protein serine/threonine phosphatases, stimulated transport activity of BGT1 but not amino acid transport system ATA2 or taurine transport (TauT). Data are mean SD of 3–7 experiments. *Significantly different () from isotonic (Iso) controls.
