Pathology Research International / 2010 / Article / Tab 1

Case Report

Cerebral Sinus Thrombosis: A Fatal Neurological Complication of Ulcerative Colitis

Table 1

Inflammatory bowel disease cases complicated by cerebral thrombosis: treatment and outcomes as reported in the reviewed literature.

ReferenceAge/SexInflammatory bowel diseaseOnset of symptoms to diagnosisInitial TreatmentLater TreatmentOutcome

Prasad et al. [16]5/FCrohn’s3 daysVenous sinus angioplasty and local tPASystemic anticoagulationComplete recovery
Philips et al. [15]35/FUC4 dayLocal Urokinase and mechanical clot macerationSystemic anticoagulationComplete recovery
Philips et al. [15]14/FIBDUnknownLocal UrokinaseSystemic anticoagulationComplete recovery
Kao et al. [12]14/FUCUnknownLocal urokinaseSystemic anticoagulationPartial resolution of symptoms
Kao et al. [12]7/FUCUnknownLMWHASAPartial resolution of symptoms
Kao et al. [12]20/FUCUnknownLMWHSystemic anticoagulationComplete recovery
Kao et al. [12]13/FUCUnknownLMWHSystemic anticoagulationComplete recovery
Wasay et al. [19]23/FUCUnknownLocal UrokinaseSystemic anticoagulationPartial resolution of symptoms
Wasay et al. [19]34/FUCUnknownLocal UrokinaseSystemic anticoagulationComplete recovery
Wasay et al. [19]29/MUCUnknownLocal UrokinaseSystemic anticoagulationPartial resolution of symptoms
Derdeyn and Powers [20]26/FUC10WarfarinSystemic anticoagulationPartial resolution of symptoms
Murata et al. [21]19/MUCUnknownHeparinUnknownComplete recovery
Samal et al. [22]20/MCrohn’s3Oral anticoagulantsUnknownPartial resolution of symptoms
Maag and Prayson [3]30/MCrohn’s1Recanalization attemptNoneDeath
Tsujikawa et al. [23]27/MUC9Heparin and UrokinaseSystemic anticoagulationComplete recovery
Srivastava et al. [24]29/MUC10LMWHSystemic anticoagulationComplete recovery
Wartenberg and Palestrant [18]43/FUC4Local thrombolysis (rTPA)Systemic anticoagulationPartial resolution of symptoms

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