Case Report
Cerebral Sinus Thrombosis: A Fatal Neurological Complication of Ulcerative Colitis
Table 1
Inflammatory bowel disease cases complicated by cerebral thrombosis: treatment and outcomes as reported in the reviewed literature.
| Reference | Age/Sex | Inflammatory bowel disease | Onset of symptoms to diagnosis | Initial Treatment | Later Treatment | Outcome |
| Prasad et al. [16] | 5/F | Crohn’s | 3 days | Venous sinus angioplasty and local tPA | Systemic anticoagulation | Complete recovery | Philips et al. [15] | 35/F | UC | 4 day | Local Urokinase and mechanical clot maceration | Systemic anticoagulation | Complete recovery | Philips et al. [15] | 14/F | IBD | Unknown | Local Urokinase | Systemic anticoagulation | Complete recovery | Kao et al. [12] | 14/F | UC | Unknown | Local urokinase | Systemic anticoagulation | Partial resolution of symptoms | Kao et al. [12] | 7/F | UC | Unknown | LMWH | ASA | Partial resolution of symptoms | Kao et al. [12] | 20/F | UC | Unknown | LMWH | Systemic anticoagulation | Complete recovery | Kao et al. [12] | 13/F | UC | Unknown | LMWH | Systemic anticoagulation | Complete recovery | Wasay et al. [19] | 23/F | UC | Unknown | Local Urokinase | Systemic anticoagulation | Partial resolution of symptoms | Wasay et al. [19] | 34/F | UC | Unknown | Local Urokinase | Systemic anticoagulation | Complete recovery | Wasay et al. [19] | 29/M | UC | Unknown | Local Urokinase | Systemic anticoagulation | Partial resolution of symptoms | Derdeyn and Powers [20] | 26/F | UC | 10 | Warfarin | Systemic anticoagulation | Partial resolution of symptoms | Murata et al. [21] | 19/M | UC | Unknown | Heparin | Unknown | Complete recovery | Samal et al. [22] | 20/M | Crohn’s | 3 | Oral anticoagulants | Unknown | Partial resolution of symptoms | Maag and Prayson [3] | 30/M | Crohn’s | 1 | Recanalization attempt | None | Death | Tsujikawa et al. [23] | 27/M | UC | 9 | Heparin and Urokinase | Systemic anticoagulation | Complete recovery | Srivastava et al. [24] | 29/M | UC | 10 | LMWH | Systemic anticoagulation | Complete recovery | Wartenberg and Palestrant [18] | 43/F | UC | 4 | Local thrombolysis (rTPA) | Systemic anticoagulation | Partial resolution of symptoms |
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