Morphologic Characteristic of Coronary Artery Disease, with Emphasis on Thromboses, in Patients Younger Than 40 Years of Age
Figure 1
Quantitation of necrotic cores in hearts from patients dying sudden with severe coronary disease. (a) The numbers of necrotic cores increased with advancing age, reaching a maximum in the sixth decade. There was a significant increase between 30 years and both the 7th and 8 decades (). (b) Adjusted for plaque burden (numbers of atheromatous plaques/total number studied), the number of fibroatheromas was similar across all ages, with the exception of under age 30, which demonstrated a significantly lower number. There was a significant increase between 30 years and the 5th decade (), the 6th decade (), and the 7th decades ().