Research Article

Placental Vascular Obstructive Lesions: Risk Factor for Developing Necrotizing Enterocolitis

Table 1

FVOL: fetal vascular obstructive lesions defined as placentae with the presence of one or more of the following lesions: MT: multiple thrombi, IT: isolated thrombus, OE: obliterative endarteritis, HEV: hemorrhagic endovasculitis. P-value*: comparison between the three different control groups and the study group*  P-value**: comparison between the very preterm control group and the very preterm study group**.

Total number of placentae FVOLType of vascular obstructive lesions
MTITOEHEV

Study group*7750 (64.9%)30 (39.0%)15 (19.5%)15 (19.5%)11 (14.3%)

Very preterm study group (<30  weeks) * *4124 (58.5%)14 (34.1%)10 (24.4%)5 (12.2%)3 (7.3%)

Control group
P-value*
769130 (16.9%)
.0001*
37 (4.8%)
.0001*
59 (7.7%)
.0021*
20 (2.6%)
.0001*
25 (3.3%)
.0002*

Preterm control group (<37  weeks)
P-value*
27947 (16.8%)
.0001*
15 (5.4%)
.0001*
27 (9.7%)
.00268*
9 (3.2%)
.0001*
7 (2.5%)
.0002*

Very preterm control group (<30  weeks)
P-value*
P-value**
5313 (24.5%)
.0001*
.0013**
7 (13.2%)
.0015*
.0237**
5 (9.4%)
.1427*
.086**
4 (7.5%)
.0772*
.049**
3 (5.7%)
.1547*
1.000**