Pleomorphic Lobular Carcinoma in a Male Breast: A Rare Occurrence
Figure 1
(a) Cut surface of the gross specimen shows circumscribed, grey white tumor with few small areas of necrosis. (b) Sections from the tumor mass show hyperchromatic, pleomorphic cells in diffuse sheets. At place cells with targetoid appearance (arrow) are noted [H & E x400]. (c) Higher magnification showing pleomorphic cells with PAS positive (arrow) intracytoplasmic mucin [PAS x400]. (d) Immunohistochemistry for E-cadherin negative [Avodin Biodin, x100].
