Table of Contents
Pathology Research International
Volume 2011, Article ID 173541, 7 pages
http://dx.doi.org/10.4061/2011/173541
Case Report

Prostatic Adenocarcinoma Metastatic to Pleomorphic Liposarcoma, a “Collision Phenomenon”: Report of a Case with Review of Pelvic Collision Tumors

1Department of Pathology, University of Pittsburgh Medical Center, A615, Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA
2Department of Urology, University of Pittsburgh Medical Center, Suite 209, Shadyside Medical Building, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
3Department of Pathology, University of Pittsburgh Medical Center (UPMC), 631E Montefiore Hospital, Pittsburgh, PA 15261, USA
4Department of Pathology, UPMC Shadyside Hospital, Room Wing 02.10, 5230 Centre Avenue, Pittsburgh, PA 15232, USA
5Department of Pathology, University of Pittsburgh Medical Center (UPMC), Room 2.9 West Wing, Shadyside, Pittsburhg, PA 15232, USA

Received 6 March 2011; Accepted 17 June 2011

Academic Editor: R. Montironi

Copyright © 2011 Somak Roy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

“Collision tumor” is an uncommon phenomenon characterized by coexistence of two completely distinct and independent tumors at the same site. Collision tumors have been reported in different sites in the body; however, these are particularly uncommon in the pelvic cavity. A 70-year-old man, with prior history of urothelial and prostate cancer, presented with a large pelvic mass detected on imaging studies. Pathological examination revealed a large liposarcoma with prostatic carcinoma embedded in it. Immunohistochemistry and florescence in situ hybridization studies were performed to reach to a conclusive diagnosis. To the best of our knowledge, this is the second case reported till date. We present the challenges encountered in the diagnosis of this case and review of pelvic collision tumors.