Pathology Research International / 2011 / Article / Tab 2

Case Report

Prostatic Adenocarcinoma Metastatic to Pleomorphic Liposarcoma, a “Collision Phenomenon”: Report of a Case with Review of Pelvic Collision Tumors

Table 2

Sequence of events.

YearSiteMorphologyIHCFISHDiagnosisTreatment

5/2003Urinary bladder diverticulumBiphasic (epithelial and spindle cells) tumor with high-grade cytologic features. ALI−, PNI−, perivesical soft-tissue invasionpanCK+, CK20+, Vimentin−, CD68−, desmin−, SMA−NASarcomatoid urothelial carcinomaPartial cystectomy, gemcitabine and carboplatin (4 cycles), intravesical BCG

10/2006ProstateProstate adenocarcinoma, Gleason’s Score 4 + 4 = 8 , ALI+, PNI+, ECE+, Seminal vesicle involvement.NANAHigh-grade prostatic adenocarcinomaRadical prostatectomy and radiotherapy

4/2010Pelvic massMyxoid liposarcoma with pleomorphic areas, characteristic lipoblasts and hyalinized stroma mingled with well-differentiated prostatic adenocarcinomaLiposarcoma: vimentin+, S100−, SMA−, desmin−, HMB45−, melan A−, myogenin−, CD117−
PCa: AE1/AE3+, CAM5.2+, weak P501S+, AR+
Liposarcoma: CHOP+, MDM2−
PCa:TMPRSS2−
ERG+
Dedifferentiated myxoid liposarcoma with embedded prostatic adenocarcinomaTumor resection, en bloc sigmoid colectomy, and ureteroneocystostomy

ALI: angiolymphatic invasion, AR: androgen receptor, CK: Cytokeratin, ECE: extracapsular extension, FISH: florescence in situ hybridization, IHC: immunohistochemistry, PCa: prostatic adenocarcinoma: PNI: perineural invasion, SMA: smooth muscle actin.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.