Morphological Analysis of CDC2 and Glycogen Synthase Kinase 3β Phosphorylation as Markers of G2 → M Transition in Glioma
Table 2
(a) CDC2 Expression Profile in GBM, astrocytoma, and oligodendroglioma. Number of cases () that showed upregulated, downregulated, and intermediate expression measures of CDC2 are illustrated. Log-ranked -values of direct comparisons between the groups are shown. Up = upregulated, down = downregulated, int = intermediate expression, -value = log ranked -value. (b) CDC2 copy numbers in GBM, astrocytoma, and oligodendroglioma. Number of cases () that showed amplified or deleted CDC2 are illustrated. >2x = more than or equal to two copies, <2x = less than or equal to two copies. Increased CDC2 copy number is associated with increased survival in GBM and astrocytoma, but not oligodendroglioma.