Morphological Analysis of CDC2 and Glycogen Synthase Kinase 3β Phosphorylation as Markers of G2 → M Transition in Glioma
Table 3
(a) Expression Profiles of CDC2 interacting proteins in GBM. Relationship of gene expression to patient survival by CDC2-interacting proteins GSK3β, CDK7/CAK, WEE1, Cyclin A2, and Cyclin B1 are illustrated. Number of cases () that showed upregulated, downregulated, and intermediate expression measures of CDC2 are illustrated. Log-ranked -values of direct comparisons between the groups are shown. Up = upregulated, down = downregulated, int = intermediate expression, -value = log ranked -value. (b) Copy numbers of CDC2 interacting proteins in GBM. Relationship of copy number of CDC2-interacting proteins GSK3β, CDK7/CAK, WEE1, Cyclin A2, and Cyclin B1 to patient survival is reported. Number of cases () that showed amplified or deleted CDC2 are illustrated. >2x = more than or equal to two copies, <2x = less than or equal to two copies.
