Benign Lesions in Mucosa Adjacent to Intestinal-Type Sinonasal Adenocarcinoma

Table 1

Histological changes in mucosa adjacent to ITAC and in controls and comparison to the literature.

		This study				[11]		[12]	[13]		[14]		[15]		[16]
	Tissue sample	Adjacent		Control		Adjacent		Adjacent	Mucosa		Mucosa		Mucosa		Mucosa
	Wood exposure	Yes	No	Yes	No	Yes	No	Yes	Yes	No	Yes	No	Yes*	No	Yes	No
	Number of samples	45	6	17	2	10	5	22	144	31	65	68	139	16	113	54
Surface; epithelium	Dysplasia	6 (13%)	1 (17%)	1 (6%)	0	0 (0%)	0 (0%)	16 (73%)	7 (5%)	1 (3%)	0 (0%)	0 (0%)	37 (27%)	0	14 (12%)	1 (2%)
	Cuboidal metaplasia	25 (56%)	4 (67%)	4 (24%)	1 (50%)			19 (86%)	40 (28%)	5 (16%)
	Squamous metaplasia	10 (22%)	2 (33%)	1 (6%)	0	0 (0%)	0 (0%)	5 (23%)	57 (40%)	16 (52%)	40 (61%)	5 (7%)	90 (65%)	2 (13%)	41 (40%)	17%
	Hyperplasia	26 (58%)	1 (17%)	4 (24%)	1 (50%)				59 (41%)	6 (19%)			30 (22%)	1 (6%)
	Intestinal metaplasia	3 (7%)	1 (17%)	0	0
Seromucinous; glands	Dysplasia	8 (18%)	2 (33%)	0	0
	Hyperplasia	14 (31%)	3 (50%)	7 (41%)	0

*Exposure to leather dust.