Benign Lesions in Mucosa Adjacent to Intestinal-Type Sinonasal Adenocarcinoma

Table 3

Histological changes and p53 expression in relation to adjacent tumor type and tumor T stage.

	Nr	Dysplasia	Cuboid	Squamous	Hyperplasia	p53 Adjacent mucosa				p53 tumor
			Metaplasia	Metaplasia		0–10%	10–25%	25–50%	50–100%	<10%	>10%
Papillary	7	1 (17%)	2 (29%)	1 (17%)	5 (83%)	2 (29%)	4 (57%)	1 (14%)	0	1 (14%)	6 (84%)
Colonic	23	5 (22%)	16 (70%)	5 (22%)	5 (22%)	16 (70%)	6 (26%)	1 (4%)	0	3 (13%)	20 (87%)
Solid	4	0	3 (75%)	0	0	2 (50%)	2 (50%)	0	0	0	4 (100%)
Mucinous	17	1 (6%)	8 (47%)	6 (35%)	6 (35%)	7 (41%)	4 (24%)	5 (29%)	1 (6%)	7 (41%)	10 (59%)
T1	15	2 (13%)	9 (60%)	2 (13%)	7 (47%)	11 (73%)	3 (20%)	1 (7%)	0	4 (27%)	11 (73%)
T2	5	1 (20%)	3 (60%)	0	2 (40%)	2 (40%)	2 (40%)	1 (20%)	0	2 (40%)	3 (60%)
T3	17	2 (12%)	9 (53%)	6 (35%)	11 (65%)	10 (59%)	5 (29%)	1 (6%)	1 (6%)	4 (24%)	13 (76%)
T4	14	2 (14%)	8 (57%)	4 (29%)	7 (50%)	4 (29%)	7 (50%)	3 (21%)	0	2 (14%)	12 (86%)

P53 immunopositivity is presented as the number of cases that showed some positivity.