Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location
Figure 2
Microscopic features of SpCC. (a) The irregular, atypical spindle cells widely distributed in a loose stroma mimicking granulation tissue. (H&E, ×100). (b) Hypercellular areas of atypical spindle cell component resembling a true fibrosarcoma. Also note those frequent mitotic figures, some of which atypical. (H&E, ×200). (c) “Transition zone of the tumor”, spindle-shaped tumor cells “dropping off” from squamous cell carcinoma. (H&E, ×400). (d) Squamous cell carcinoma component of tumor showing Pan-CK positivity. (Pan CK, ×200). (e) Vimentin positivity in sarcomatoid component. (Vimentin, ×200). (f) Ki-67 staining of stromal spindle cells. (Ki-67, ×400).
