Review Article

Fine-Needle Aspiration Biopsy of Hepatocellular Carcinoma and Related Hepatocellular Nodular Lesions in Cirrhosis: Controversies, Challenges, and Expectations

Figure 6

FNA of hepatocellular carcinoma. (a) Two populations of malignant hepatocytes are seen. One population forms a distinct broad trabecula with peripheral endothelium. The other tumor cells are bigger, more pleomorphic, and less cohesive (Papanicolaou, ×200). (b) The more pleomorphic cells appear discohesive but still retain recognizable hepatocytic characteristics. Note transgressing endothelium (Papanicolaou, ×400). (c) Cell block shows trabecular-sinusoidal and pseudoacinar patterns. (H&E, ×200).
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(a)
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(b)
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(c)