Fine-Needle Aspiration Biopsy of Hepatocellular Carcinoma and Related Hepatocellular Nodular Lesions in Cirrhosis: Controversies, Challenges, and Expectations
Figure 8
FNA of poorly differentiated hepatocellular carcinoma. (a) Two populations of tumor cells are seen. The better differentiated component is represented by a trabecula of malignant hepatocytes with peripheral endothelium. The other population consists of highly pleomorphic tumor cells with giant cells and bizarre nuclei; there is no apparent resemblance to hepatocytes (Papanicolaou, ×200). (b) Highly pleomorphic tumor giant cells exhibit multinucleation, bizarre nuclei, and hyperchromatism (Papanicolaou, ×400).
