Figure 2: Case  12. (a) CS method. A loosely cohesive and crowded tissue fragment displays malignant cells, which have sharp-ended nuclei with enlarged nucleoli, in the myxoid and collagenized matrix, as considered to be adenocarcinoma. (b) TP method. A small number of clusters with irregularly crowded atypical cells are observed in the background, which is clean and devoid of single cells. Since no other such a cluster was observed in the specimen, this case was diagnosed as AGC (Papanicolaou; original magnification, x600, resp.).