Fatal Hemothorax Caused by Pseudomesotheliomatous Carcinoma of the Lung
Figure 2
Histological and immunophenotypic features of the tumor: interstitial infiltrating growth pattern of a poorly differentiated carcinoma ((a), detail in (b)) with atypical BAC-like pneumocytes lining the alveoli in (b) and around (a) the interstitial component of the tumor (HE). The visceral pleura shows a cake of highly vascularized and poorly cohesive carcinoma ((c), HE), with cytonuclear features similar to the interstitial infiltrating tumor in the lung. (d) The tumor invades into a medium-size vessel (elastica van Gieson stain). There is strong immunoreactivity for CAM5.2 (e) and TTF-1 (f) in the atypical BAC-like component and variable immunoreactivity for CAM5.2 (e) and TTF-1 (f) in the infiltrating carcinoma.
