Disease Extent ≥4 cm Is a Prognostic Marker of Local Recurrence in T1-2 Breast Cancer
Table 1
Patents and tumor characteristics.
Characteristic
All
Extensive
Non extensive
≥4 cm
<4 cm
valuea
Number of patients
313
44
269
Age
Median
61.2
59.4
61.5
0.162
Mean
61.0
58.7
61.4
Disease extent
≥4 cm
44
44
≥3 cm
36
36
≥2 cm
70
70
<2 cm
163
163
Size of dominating tumor mass
≥15 mm
180
29
151
0.224
<15 mm
133
15
118
T-classification
T1
211
22
189
0.045
T2
36
8
28
T3 or T4
0
0
0
Local recurrence
Yes
27
9
18
0.003
No
276
35
251
Follow-up time (months)
Median
120
120
120
0.108
Mean
106
95
108
Min
3
14
3
Max
120
120
120
Grade of invasive lesion
I
93
10
83
0.900
II
107
13
94
III
45
6
39
Missing
68
15
53
Grade of in situ lesion
I
109
16
93
0.005
II
99
8
91
III
59
16
43
Missing
46
4
42
Radiotherapy
Yes
206
28
178
0.736
No
93
14
79
Missing
14
2
12
Hormonal therapy
Yes
52
11
41
0.101
No
196
24
172
Missing
65
9
56
Chemotherapy
Yes
22
3
19
0.946
No
226
32
194
Missing
65
9
56
Estrogen receptor status
Positive
215
26
189
0.704
Negative
28
4
24
Progesterone receptor status
Positive
171
22
149
0.759
Negative
70
8
62
aTest of variable distribution between patients with extensive versus nonextensive tumors, using either a Mann Whitney test or a chi-square test where appropriate.
