Table of Contents
Pathology Research International
Volume 2012, Article ID 483670, 6 pages
http://dx.doi.org/10.1155/2012/483670
Clinical Study

Automated Measurement of Immature Granulocytes: Performance Characteristics and Utility in Routine Clinical Practice

1Department of Pathology, Chettinad Deemed University, Padur, Kancheepuram 603103, India
2Chettinad Deemed University, Padur, Kancheepuram 603103, India
3Department of Microbiology, Chettinad Deemed University, Padur, Kancheepuram 603103, India

Received 26 September 2011; Accepted 30 November 2011

Academic Editor: H. A. Lehr

Copyright © 2012 Balamurugan Senthilnayagam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. A. Ansari-Lari, T. S. Kickler, and M. J. Borowitz, “Immature granulocyte measurement using the sysmex XE-2100: relationship to infection and sepsis,” American Journal of Clinical Pathology, vol. 120, no. 5, pp. 795–799, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. W. Van Der Meer, W. Van Gelder, R. De Keijzer, and H. Willems, “Does the band cell survive the 21st century?” European Journal of Haematology, vol. 76, no. 3, pp. 251–254, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. K. G. Nigro, M. O'Riordan, E. J. Molby, M. C. Walsh, and L. M. Sandhaus, “Performance of an automated immature granulocyte count as a predictor of neonatal sepsis,” American Journal of Clinical Pathology, vol. 123, no. 4, pp. 618–624, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Buttarello and M. Plebani, “Automated blood cell counts: state of the art,” American Journal of Clinical Pathology, vol. 130, no. 1, pp. 104–116, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. D. -H. Park, K. Park, J. Park et al., “Screening of sepsis using leukocyte cell population data from the Coulter automatic blood cell analyzer DxH800,” International Journal of Laboratory Hematology, vol. 33, no. 4, pp. 391–399, 2011. View at Publisher · View at Google Scholar
  6. F. Chaves, B. Tierno, and D. Xu, “Quantitative determination of neutrophil VCS parameters by the Coulter automated hematology analyzer: new and reliable indicators for acute bacterial infection,” American Journal of Clinical Pathology, vol. 124, no. 3, pp. 440–444, 2005. View at Publisher · View at Google Scholar
  7. B. Fernandes and Y. Hamaguchi, “Automated enumeration of immature granulocytes,” American Journal of Clinical Pathology, vol. 128, no. 3, pp. 454–463, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. B. Fernandes and Y. Hamaguchi, “Performance characteristics of the Sysmex XT-2000i hematology analyzer,” Laboratory Hematology, vol. 9, no. 4, pp. 189–197, 2003. View at Google Scholar · View at Scopus
  9. D. Field, E. Taube, and S. Heumann, “Performance evaluation of the immature granulocyte parameter on the sysmex XE-2100 automated hematology analyzer,” Laboratory Hematology, vol. 12, no. 1, pp. 11–14, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Briggs, S. Kunka, H. Fujimoto, Y. Hamaguchi, B. H. Davis, and S. J. Machin, “Evaluation of immature granulocyte counts by the XE-IG Master: upgraded software for the XE-2100 automated hematology analyzer,” Laboratory Hematology, vol. 9, no. 3, pp. 117–124, 2003. View at Google Scholar · View at Scopus
  11. CLSI . H20-A2 Reference Leukocyte (WBC) Differential Count (Proportional) and Evaluation of Instrumental Methods, Clinical Laboratory and Standards Institute, Wayne, Pa, USA, 2nd edition, 2007.
  12. A. K. Akobeng, “Understanding diagnostic tests 3: receiver operating characteristic curves,” Acta Paediatrica, vol. 96, no. 5, pp. 644–647, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. M. H. A. Roehrl, D. Lantz, C. Sylvester, and J. Y. Wang, “Age-dependent reference ranges for automated assessment of immature granulocytes and clinical significance in an outpatient setting,” Archives of Pathology and Laboratory Medicine, vol. 135, no. 4, pp. 471–477, 2011. View at Google Scholar
  14. M. Bruegel, G. M. Fiedler, G. Matthes, and J. Thiery, “Reference values for immature granulocytes in healthy blood donors generated on the Sysmex XE-2100 automated hematology analyser,” Sysmex Journal International, vol. 14, no. 1, pp. 5–7, 2004. View at Google Scholar
  15. F. K. Sáenz, G. L. Narváez, M. Cruz, and C. Checa, “Immature granulocytes reference values, using the sysmex XE-2100 blood counter,” Revista Mexicana de Patología Clínica, vol. 57, no. 4, 2010. View at Google Scholar
  16. D. P. Frings, B. Montag, A. Heydorn, M. Friedemann, W. Pothmann, and A. Nierhaus, “Immature granulocytes, immature myeloid cells and outcome in adult severe sepsis and septic shock,” in Proceedings of the 16th Annual Congress of the European Society of Intensive Care Medicine (ESICM '03), Amsterdam, Netherlands, October 2003.
  17. C. Iddles, J. Taylor, R. Cole et al., “Evaluation of immature granulocyte count in the diagnosis of sepsis using the Sysmex XE-2100 analyser,” Sysmex Journal International, vol. 17, pp. 20–29, 2007. View at Google Scholar
  18. Th. Weiland, H. Kalkman, and H. Heihn, “Evaluation of the automated immature granulocyte count (IG) on sysmex XE-2100 automated haematology analyser vs. visual microscopy (NCCLS H20-A),” Sysmex Journal International, vol. 12, pp. 63–70, 2002. View at Google Scholar