Automated Measurement of Immature Granulocytes: Performance Characteristics and Utility in Routine Clinical Practice

Table 4

Performance characteristics at different cut-off values.

	Cutoff	Sensitivity	95% CI	Specificity	95% CI	+LR	−LR
Adults
IGC
Optimised	0.11	66.67	46–83.5	78.67	67.7–87.3	3.12	0.42
Roehrl et al.	0.07	70.37	49.8–86.2	57.33	45.4–68.7	1.65	0.52
Bruegel et al.	0.03	81.48	61.9–93.7	33.33	22.9–45.2	1.22	0.56
Institutional	0.1	66.67	46–83.5	78.67	67.7–87.3	3.12	0.42
IG%
Optimised	1.1	70.37	49.8–86.2	62.67	50.7–73.6	1.88	0.47
Roehrl et al.	0.9	70.37	49.8–86.2	58.67	46.7–69.9	1.7	0.51
Bruegel et al.	0.5	88.89	70.8–97.6	37.33	26.4–49.3	1.42	0.30
Institutional	1	70.37	49.8–86.2	62.67	50.7–73.6	1.88	0.47
Children
IG%
Optimised	>0.5	95.83	78.9–99.9	21.62	12.9–32.7	1.22	0.19
Roehrl et al.	0.3	100	85.8–100	31.51	6.7–23.5	1.16	0
IGC
Optimised	>0.1	70.83	48.9–87.4	54.1	42.1–65.7	1.54	0.54
Roehrl et al.	0.04	87.5	67.6–97.3	21.62	12.9–32.7	1.12	0.58