Research Article
Correlation of CK5 and EGFR with Clinicopathological Profile of
Triple-Negative Breast Cancer
Table 2
Correlation of EGFR and CK5 with clinicopathological variables.
| (a) |
| | Prognostic parameters | EGFR | value |
CK5 | value | | Positive | Negative | Positive | Negative |
| | Age | | ≤40 | 13 | 1 | >0.05 | 7 | 7 | >0.05 | | 41–50 | 8 | 2 | 6 | 4 | | >50 | 10 | 2 | 9 | 3 |
| | Tumor size (cm) | | ≤2 | 11 | 2 | >0.05 | 9 | 4 | >0.05 | | 2.1–5 | 15 | 3 | 11 | 7 | | >5 | 5 | 0 | 2 | 3 |
| | Histopathological diagnosis | | IDC, NOS | 24 | 5 | >0.05 | 17 | 12 | >0.05 | | Mucinous carcinoma | 2 | 0 | 1 | 1 | | Metaplastic carcinoma | 1 | 0 | 1 | 0 | | Medullary carcinoma | 3 | 0 | 3 | 0 | | Mixed ductal-lobular carcinoma | 1 | 0 | 0 | 1 |
| | Tumour grades | | Grade I | 4 | 1 | >0.05 | 2 | 3 | 0.052 | | Grade II | 17 | 0 | 8 | 9 | | Grade III | 10 | 4 | 12 | 2 |
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| (b) |
| | Prognostic parameters | EGFR | value | CK5/6 | value |
| | Tumour stage | | Stage I | 5 | 0 | >0.05 | 2 | 3 | >0.05 | | Stage II | 12 | 4 | 11 | 5 | | Stage III | 12 | 1 | 7 | 6 | | Stage IV | 2 | 0 | 2 | 0 |
| | Margins | | Infiltrative | 22 | 3 | >0.05 | 13 | 12 | >0.05 | | Pushing margin | 9 | 2 | 9 | 2 |
| | Necrosis | | Present | 12 | 4 | >0.05 | 11 | 5 | >0.05 | | Absent | 19 | 1 | 11 | 9 |
| | Infiltrate | | Present | 20 | 3 | >0.05 | 15 | 8 | >0.05 | | Absent | 11 | 2 | 7 | 6 |
| | Lymph node metasatases | | Absent | 11 | 1 | >0.05 | 6 | 6 | >0.05 | | 1 to 3 | 11 | 3 | 11 | 3 | | >4 | 9 | 1 | 5 | 5 |
| | Ki-67 | | Positive | 25 | 4 | >0.05 | 16 | 13 | >0.05 | | Negative | 6 | 1 | 6 | 1 |
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