Research Article

In Vitro Studies on the Antioxidant Property and Inhibition of α-Amylase, α-Glucosidase, and Angiotensin I-Converting Enzyme by Polyphenol-Rich Extracts from Cocoa (Theobroma cacao) Bean

Table 3

EC50 values of SNP and Fe2+ induced lipid peroxidation in rat’s pancreas, angiotensin-I converting enzyme inhibitory activity in the lungs and heart, and -amylase and -glucosidase inhibitory activity of aqueous extract of cocoa bean.

ParameterEC50 value (mg/mL)

SNP induced lipid peroxidation11.47 ± 1.07
Fe2+ induced lipid peroxidation2.12 ± 0.10
ACE (lungs)0.674 ± 0.06
ACE (heart)1.006 ± 0.08
-amylase1.81 ± 0.22
-glucosidase1.84 ± 0.17

Values represent means ± standard deviation of triplicate readings.