Table 3: Immunoexpression of the markers according to tumors invasiveness.

Muscle-invasive UC (pT2–pT4)Non-muscle-invasive UC (pTa-pT1) value

HER2
 0440.252
 1311
 229
 344

EGFR
 Negative10170.308
 Positive311

pAKT
 Nuclear positive1680.790
 Nuclear negative512

pAKT
 Cytopl positive290.315
 Cytopl negative1119

pmTOR
 Negative9100.045
 Positive418

PTEN
 Nuclear positive180.120
 Nuclear negative1219
 Missing data01

PTEN
 Cytopl positive3180.01
 Cytopl negative109
 Missing data01

e-cadherin
 Negative4120.668
 Positive613
 Missing data33

p-cadherin
 Negative4160.307
 Positive59
 Missing data43

b-catenin
 Negative280.518
 Positive817
 Missing data33

Cytopl: cytoplasmic; UC: urothelial carcinomas.