High Expression of Galectin-3 in Patients with IgG4-Related Disease: A Proteomic Approach

Figure 4

IgG4 and galectin-3 levels in serum after steroid treatment. (a) ELISA assay indicates that galectin-3 levels in serum in patients with IgG4-RD were 2- and 2.5-fold higher, before and after steroid treatment, respectively, compared to the normal control (). Error bars, standard error of the mean (SEM). Tx, treatment. (b) Changes in IgG4 and galectin-3 levels in serum of five IgG4-RD patients before and during steroid treatment. (c) Galectin-3 levels in serum in five steroid-treated IgG4-RD patients. Galectin-3 levels were 1.39-fold higher immediately after the start of the treatment (mean 1 month) and 1.37-fold higher at the last follow-up treatment after 24 months on average, compared to the pretreatment levels.

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