Research Article
The Role of Osteocalcin and Alkaline Phosphatase Immunohistochemistry in Osteosarcoma Diagnosis
Table 2
Immunoreactivity of osteocalcin and alkaline phosphatase in osteosarcoma and other primary bone tumour.
| | Tumor type | Total no. | OCN () | ALP () | | Positive | Negative | Positive | negative |
| | Conventional OSA | 25 | 17 | 8 | 24 | 1 | | Chondroblastic | 4 | 2 | 2 | 4 | 0 | | Fibroblastic | 1 | 0 | 1 | 0 | 1 | | NOS | 20 | 15 | 5 | 20 | 0 | | OPBT | 25 | 16 | 9 | 5 | 20 | | Angiosarcoma | 2 | 0 | 2 | 0 | 2 | | Chondrosarcoma | 13 | 11 | 2 | 5 | 8 | | Chordoma | 3 | 1 | 2 | 0 | 3 | | Ewing’s sarcoma | 3 | 3 | 0 | 0 | 3 | | Low grade fibromyxoid sarcoma | 1 | 0 | 1 | 0 | 1 | | Malignant giant cell tumor | 1 | 0 | 1 | 0 | 1 | | Plasmacytoma | 2 | 1 | 1 | 0 | 2 |
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OCN, Osteocalcin; ALP, Alkaline Phosphatase; OSA, Osteosarcoma; NOS, not otherwise specified; OPBT, Other Primary Bone Tumor.
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