Pathology Research International

Head and Neck Pathology: New Developments in the Diagnosis and Pathogenesis of Head and Neck Tumors


Publishing date
15 May 2011
Status
Published
Submission deadline
15 Nov 2010

1Department of Pathology, University of Virginia Charlottesville, VA 22908, USA

2Division of Oral Pathology, University of Minnesota, Minneapolis, MN 55455, USA

3Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, The Methodist Hospital Physicians Organization, Houston, TX 77030, USA


Head and Neck Pathology: New Developments in the Diagnosis and Pathogenesis of Head and Neck Tumors

Description

The neoplastic pathology of the head and neck is characterized by a wide variety of tumor types and histologic variants. Recent evidence has shown that in addition to physical and chemical carcinogens, viral infections such as EBV, HPV, and Merkel cell polyomavirus(MCV), specific translocations play an important etiologic role in some tumors, such as poorly differentiated sinonasal carcinomas [t(15;19)] and mucoepidermoid carcinomas [t(11;19)]. HPV is significant etiologic factor in a subset of squamous cell carcinomas of the head and neck; however, optimal HPV detection methods and the impact of HPV positivity on the selection of treatment modalities are less well understood. Recent evidence has shown that some of the “idiopathic” pseudotumoral lesions of the head and neck are members of the group of IgG4-related sclerosing diseases; however more research is needed to determine exact diagnostic and differential diagnostic criteria for these lesions.

We invite investigators to contribute original research articles and review articles focusing on the pathogenesis, cytogenetics, and molecular pathology of head and neck neoplasms and their precursors, as well as their early detection, chemoprevention, and prediction of treatment success. We are particularly interested in articles describing implications of new diagnostic tools in head and neck malignancies and their precursors and the impact of new cytogenetic and molecular pathologic data for the better understanding and diagnosis of head and neck malignancies. Potential topics include, but are not limited to:

  • Recent advances in oral and upper aerodigestive tract dysplasia
  • Poorly differentiated neoplasms of the sinonasal area
  • IgG4-related lesions of the head and neck: a new look at “inflammatory pseudotumors” of the head and neck
  • New developments in the pathogenesis and progression through dedifferentiation of salivary gland tumors
  • New developments in HPV-related head and neck tumors
  • Clinically significant and diagnostically challenging variants of SCC
  • Recent advances in the study of lymphangiogenesis and angiogenesis in head and neck tumors of the head and neck
  • Predictors of chemoradiation response in squamous cell carcinomas of the head and neck

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/pri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 354747
  • - Editorial

Head and Neck Pathology: New Developments in the Diagnosis and Pathogenesis of Head and Neck Tumors

Stefan E. Pambuccian | Edward B. Stelow | ... | Michael J. Thrall
  • Special Issue
  • - Volume 2011
  • - Article ID 325965
  • - Review Article

Current Concepts on Dedifferentiation/High-Grade Transformation in Salivary Gland Tumors

Ana Flávia Costa | Albina Altemani | Mario Hermsen
  • Special Issue
  • - Volume 2011
  • - Article ID 632493
  • - Research Article

Raman Spectroscopic Methods for Classification of Normal and Malignant Hypopharyngeal Tissues: An Exploratory Study

Parul Pujary | K. Maheedhar | ... | Kailesh Pujary
  • Special Issue
  • - Volume 2011
  • - Article ID 806345
  • - Research Article

Human Papillomavirus and Oropharyngeal Squamous Cell Carcinoma: A Case-Control Study regarding Tobacco and Alcohol Consumption

F. Farshadpour | S. Konings | ... | J. A. Kummer
  • Special Issue
  • - Volume 2011
  • - Article ID 934350
  • - Clinical Study

Salivary Gland Tumors in Maxillofacial Region: A Retrospective Study of 130 Cases in a Southern Iranian Population

Mahmoud Shishegar | Mohamad J. Ashraf | ... | Amir Ashrafi
  • Special Issue
  • - Volume 2011
  • - Article ID 138469
  • - Review Article

Ancillary Studies in Determining Human Papillomavirus Status of Squamous Cell Carcinoma of the Oropharynx: A Review

Richard L. Cantley | Eleonora Gabrielli | ... | Guy Petruzzelli
  • Special Issue
  • - Volume 2011
  • - Article ID 431246
  • - Review Article

Oral Carcinogenesis and Oral Cancer Chemoprevention: A Review

Takuji Tanaka | Mayu Tanaka | Takahiro Tanaka
  • Special Issue
  • - Volume 2011
  • - Article ID 230147
  • - Research Article

Benign Lesions in Mucosa Adjacent to Intestinal-Type Sinonasal Adenocarcinoma

Blanca Vivanco | José Luis Llorente | ... | Mario A. Hermsen