Glutaminase Immunoreactivity and Enzyme Activity Is Increased in the Rat Dorsal Root Ganglion Following Peripheral Inflammation
Figure 2
Image analysis of glutaminase (GLS) immunoreactivity (IR) in L4 DRG neurons after 7 days of AIA in the hindpaw. Data are presented as intensity divided by the area of the cell. DRG neurons were categorized into three area size groups: (a) small: 100–600 μm2, (b) medium: 600–1200 μm2, (c) large: >1200 μm2. (a) Small-sized neurons in DRG from AIA rats contained a significantly greater GLS immunoreactive signal (**) than controls. (b) Medium-sized neurons in DRG from AIA rats contained a significantly greater immunoreactive signal (**) than controls. (c) Large-sized neurons in DRG from AIA rats were more intensely stained than controls (*).
