Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome

Table 1

Stress-related genes studied for DNA or mRNA effects in FMS, CFS, or related disorders.

Adrenergic receptors		α-1, α-2A, α-2C, β-1, β-2, β-3
Catechol-O-methyltransferase		COMT
Cytokines		IL6, IL10, LTa, CD14, TLR4
Dopamine receptors, enzyme, and transporter		DRD1, DRD2, DRD3, DRD4, DBH, SLC6A3
Glucocorticoid and mineralocorticoid receptors		NR3C1, NR3C2
Ion channels	Purinergic	P2X4, P2X5, P2X7
	Acid sensing	ASIC1a, ASIC3
	Transient vanilloid receptor	TRPV1
Opioid receptors (kappa and delta)		OPRK1, OPRD1
Serotonin receptors, synthesis gene and transporter		HTR2a, HTR3a, HTR3b, TPH2, SLC6A4