Plasma Amino Acids Changes in Complex Regional Pain Syndrome

Table 3

Plasma neopterin, cortisol, global arginine bioavailability ratio, and L-kynurenine to L-tryptophan ratio.

Analyte	Controls	CRPS	𝑃
	(𝑛=60)	(𝑛=160)
GABR	0.727±0.037	𝟎.𝟒𝟑𝟕±𝟎.𝟎𝟏𝟖	𝟏.𝟎×𝟏𝟎^−𝟎𝟗
L-Kyn/L-Trp	0.043±0.001	𝟎.𝟎𝟓𝟎±𝟎.𝟎𝟎𝟏	0.00097
Neopterin (nM)	5.97±0.22	𝟔.𝟕𝟔±𝟎.𝟐𝟎	0.01245
Cortisol (ng/mL)	92.51±7.81	87.08±4.00	0.56200

This table lists the global arginine bioavailability ratio (GABR) (defined as plasma L-arginine/(L-ornithine + L-citrulline), the plasma L-kynurenine to L-tryptophan ratio, and the plasma levels of neopterin and cortisol in CRPS and healthy control subjects. Values are given as the mean ± the standard error of the mean. Significant difference between the control and CRPS groups was determined with the Student’s 𝑡-test. Statistically significant probability values (𝑃<0.05) are highlighted in bold.